The spaceship Serenity lets passengers travelling to another planet on board, but the strangers have secrets that cause the crew difficulties.
The Serenity crew is tricked into pulling a train robbery by a fearsome gangster. Meanwhile, River's life is in danger when two operatives chase her.
The crew searches a derelict colony ship for salvage, only to find the original crew were killed by Reavers and the vessel isn't entirely deserted.
The crew is hired to smuggle some unusual cargo during a royal ball, but Mal, defending Inara's honour, finds himself challenged to a duel.
On an outlying planet, Simon is kidnapped by the locals, who need a doctor. Meanwhile, River is caught and threatened with being burnt as a witch.
Mal is unwittingly married off to a girl from a backwater planet. His new 'wife' stows away on the ship, leaving Mal with a tough decision to make.
Jayne discovers he is a hero in a small colony he robbed years ago when the crew arrives for another heist. Will his new-found fame go to his head?
When an engine explodes on the Serenity, the oxygen supply dwindles, leaving Mal experiencing strange flashbacks about how he came to own the ship.
Simon smuggles River into a hospital to find out what the Alliance did to her, but their presence soon attracts some unwanted Alliance attention.
Wash and Mal are kidnapped and tortured by crime lord Niska while on a mission to sell stolen medical supplies. Can the Serenity crew save them?
Mal meets his ex-wife Saffron who offers him the chance to make a handsome profit by stealing a priceless antique, but the crew think it's a trick.
Mal and Zoe receive the dead body of a former war ally and are instructed to return the corpse to his family. However, all is far from what it seems.
One of Inara's friends sends a distress call to the Serenity when a heinous criminal on the moon of Deadwood tries to kidnap a baby he claims is his.
A bounty hunter named Jubal Early sneaks on board the Serenity to capture River and Simon and return them to the Alliance for the bounty.